She has a severe untreated case of a condition called kyphosis, which is a type of scoliosis. Once the condition is that advanced people don't live very long due to the pressure it puts on your internal organs. This picture was probably taken in a hospital after she was taken there by whoever was neglecting her. She probably died soon there after.

Edit: Hm. You know, I didn't think of Marfans. It could be severe Marfans. Which is also a bone disorder.