That would make for a killer Sitcom.

EDIT: I came up with a short description:

Will Ferrell plays the role of Bill Clinton, the gracefully aged former president. Upon his return to the White House, he takes the role of "First Lady" a bit too seriously, adopting a metrosexual lifestyle and rambunctious personality. His cohort, the White House Secretary of Press Jay Carney, is played by Steve Carrell, who is just stupid enough to be a part of Bill's crazy plots to take over the world. The White House Chef would be played by David Koechner, who would use his in-depth knowledge of the White House and access to backdoor in Washington DC (side catering business) to enable their plots. Yvette Nicole Brown would play the role of the Vice President (Hillary would totally select a loudmouthed black lady as VP), who would actually be the sole voice of reason in each episode, catching onto Bill's plans and trying to warn everybody, but nobody believes her until they're comically busted at the end of each episode. Finally, a love interest with Zooey Deschanel, a quirky yet adorable White House tour guide who has started to catch onto Bill's shenanigans.

It would be like a cross between Pinky and the Brain, Anchorman, Two and a Half Men, Oceans 11, and Phineas and Ferb.